Taeho Lee Selected Research

PF-543

5/2020	Verification of the Necessity of the Tolyl Group of PF-543 for Sphingosine Kinase 1 Inhibitory Activity.
1/2019	Synthesis and Biological Evaluation of PF-543 Derivative Containing Aliphatic Side Chain.
1/2018	Synthesis of dansyl labeled sphingosine kinase 1 inhibitor.

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Taeho Lee Research Topics

Disease

16	Neoplasms (Cancer) 01/2022 - 06/2012
7	Inflammation (Inflammations) 09/2019 - 05/2013
5	Sepsis (Septicemia) 04/2020 - 03/2013
4	Infections 12/2015 - 05/2013
3	Metabolic Diseases (Metabolic Disease) 05/2021 - 01/2019
2	Obesity 05/2021 - 01/2019
2	Atopic Dermatitis (Atopic Eczema) 01/2020 - 08/2014
2	Alzheimer Disease (Alzheimer's Disease) 06/2019 - 09/2016
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 01/2018
2	Insulin Resistance 01/2019 - 01/2019
2	Periodontitis 01/2018 - 01/2017
2	Multiple Sclerosis 01/2018 - 01/2018
2	Carcinoma (Carcinomatosis) 01/2017 - 08/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2016 - 06/2013
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	Body Weight (Weight, Body) 12/2021
1	Hypernatremia 12/2021
1	Diabetes Mellitus 05/2021
1	Lung Injury 10/2020
1	Pulmonary Edema 10/2020
1	Pain (Aches) 09/2019
1	Stomach Neoplasms (Stomach Cancer) 01/2019
1	Hyperglycemia 01/2019
1	Hypersensitivity (Allergy) 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2019
1	Myocardial Infarction 01/2018
1	Alveolar Bone Loss 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2017
1	Ototoxicity 05/2017
1	Hearing Loss (Hearing Impairment) 05/2017
1	Hypoxia (Hypoxemia) 01/2017
1	Hepatocellular Carcinoma (Hepatoma) 01/2017
1	Bone Resorption 01/2017
1	Wounds and Injuries (Trauma) 07/2016

Drug/Important Bio-Agent (IBA)

3	CytokinesIBA 10/2020 - 05/2013
3	PF-543IBA 05/2020 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 04/2020 - 09/2016
3	HMGB1 Protein (HMG1)IBA 04/2020 - 03/2013
3	AntioxidantsIBA 05/2017 - 06/2012
2	sphingosine kinaseIBA 01/2022 - 05/2020
2	Drinking WaterIBA 12/2021 - 08/2014
2	sphingosine phosphorylcholineIBA 01/2020 - 08/2014
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2020 - 12/2019
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 06/2019 - 09/2016
2	pyruvate dehydrogenase kinase 4IBA 03/2019 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2014
2	Fingolimod Hydrochloride (FTY720)FDA Link 10/2018 - 01/2018
2	TriazolesIBA 05/2017 - 12/2015
2	EnzymesIBA 01/2017 - 08/2014
2	Cytochrome P-450 CYP2J2 (CYP2J2)IBA 01/2017 - 08/2014
2	AcidsIBA 07/2016 - 08/2014
1	GTP-Binding Proteins (G-Protein)IBA 01/2022
1	Phosphates (Orthophosphate)IBA 01/2022
1	LipidsIBA 01/2022
1	sulfurylase kinaseIBA 01/2022
1	SphingolipidsIBA 01/2022
1	SphingosineIBA 01/2022
1	Contrast MediaIBA 01/2022
1	Arginine Vasopressin (Argipressin)IBA 12/2021
1	Orphan Nuclear ReceptorsIBA 05/2021
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 01/2021
1	Autophagy-Related ProteinsIBA 10/2020
1	cardamoninIBA 10/2020
1	Particulate MatterIBA 10/2020
1	Toll-Like Receptor 2IBA 10/2020
1	Beclin-1IBA 10/2020
1	TOR Serine-Threonine KinasesIBA 10/2020
1	Peroxidase (Myeloperoxidase)IBA 10/2020
1	Local Anti-Infective Agents (Antiseptics)IBA 04/2020
1	SphingomyelinsIBA 01/2020
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2020
1	Biological ProductsIBA 01/2020
1	CeramidesIBA 01/2020
1	sphingomyelin deacylaseIBA 01/2020
1	MitogensIBA 01/2020
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2020
1	loxoprofen (CS 600)IBA 09/2019
1	Cyclooxygenase InhibitorsIBA 09/2019
1	Methanol (Carbinol)IBA 06/2019
1	SuspensionsIBA 06/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	interferon regulatory factor-8 (interferon consensus sequence binding protein)IBA 01/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2019
1	benzamideIBA 01/2018
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2017
1	Cisplatin (Platino)FDA LinkGeneric 05/2017
1	Gefitinib (Iressa)FDA Link 01/2017
1	LuciferasesIBA 01/2017
1	ElementsIBA 01/2017
1	Small Molecule LibrariesIBA 01/2017
1	acetylshikoninIBA 01/2017
1	pyrimidineIBA 01/2017
1	OCLI-023IBA 01/2017
1	Amyloid (Amyloid Fibrils)IBA 09/2016
1	Pentacyclic TriterpenesIBA 07/2016

Therapy/Procedure

4	Ligation 04/2020 - 01/2017
2	Punctures 04/2020 - 01/2018
1	Transplantation 01/2019
1	Therapeutics 01/2017